Outputs from the ISARIC 4C consortium

This page is intended to provide updates for participants on the work that has been done with their samples and data. We will keep this page updated with research results, reports and plans.

During its first 3 months, the ISARIC 4C consortium expanded from the initial 34 co-investigators to more than 150 active contributors, and provides a data and sampling infrastructure for follow-up of COVID cases in the P-HOSP consortium.

Outputs

Risk prediction: the 4C Score

BMJ 2020;370:m3339 The ISARIC 4C prognostic score Using data from 57,824 hospital admissions, w...

T cell activation

Nature Immunology (4th September 2020) Immune cells target many different parts of the virus ...

Characterisation of hospitalised cases of COVID-19

BMJ: 2020; 369 Quantifying the problem Within weeks of being funded, we produced the largest st...

Impact on children

BMJ 2020;370:m3249 Clinical characterisation of Covid-19 in children We have comprehensively ch...

Symptom clusters

MedRxiv August 16th 2020. Because of the large scale of the ISARIC-4C study, we were able to d...

Ethnicity

SSRN July 2020 Impact of ethnicity We have carefully studied the effect of ethnicity on outcome...

Testing the tests

MedRxiv May 2020 We proposed and established a Diagnostic Evaluation Platform at the University ...

ICECAP autopsy study

MedRxiv June 2020 Supporting autopsy work ISARIC 4C resources and consortium partners supported...

Setting Serology Standards

Setting the standard ISARIC 4C defined the international reference standard for SARS-CoV-2 serol...

Transmission

Medrxiv June 2020 Transmission dynamics of COVID-19 We have explored the mechanisms of viral tr...